Vinpocetine is a semisynthetic drug that contains Vinca minor extracts from the periwinkle plant. It is a vasodilator, meaning it increases the amount of blood flow within the cerebral cotrex thus, improving memory and cognition. Some suggest that it may have neuroprotective properties and improve memory impairment associated with aging. It also has anti-inflammatory effects, which may make it useful in combating symptoms of neurodegenerative disorders. Several clinical trials have been conducted with this drug on those with neurodegenerative disorders, but results are controversial. It works via the inhibition of voltage-sensitive sodium channels, thus preventing damage to neurons. It is considered tolerable in humans, but the tolerability over the long-term is unknown.
Vinpocetine is categorized under Metabolic Enhancers.
It is also known as Vincamine, Vinca Minor, Periwinkle Extract, Cavinton Brand Name, ethyl apovincaminate.
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Benefits and Effectiveness
What is Vinpocetine?
Vinpocetine for Improved Cognition and Mental Energy
Are you looking for a natural nootropic that could actually cater to a number of your needs? Whether it be an enhanced cognitive function, an improved mood, or a generally healthy brain, then Vinpocetine is the answer. Known to be one of the safest nootropics today, Vinpocetine is a popular supplement that can be added to your daily regime and can be used in a long-term basis. Aside from that, you can find Vinpocetine from the most commonly recommended and powerful stacks such as the Alpha Brain.
This nootropic is actually one of your best options if you are looking for an excellent study aid. Let us now look at what Vinpocetine has to offer and why it is considered one of the best.
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What are the benefits of Vinpocetine and its mechanism of action?
1. Improved blood flow to the brain
This is probably the most important mechanism that Vinpocetine has to offer- an enhanced blood circulation to the brain. But unlike the other vasodilators such as Adderall and Ephedrine, Vinpocetine is unique since it is specific to the brain only. It improves only the brain’s blood circulation while not affecting the body’s blood pressure. Aside from that, it targets the damaged brain cells and the areas deficient of proper blood circulation. With an improved blood circulation, there would also be improvement in oxygen and glucose uptake thus, enhancing one’s cognitive functions.
With regards to the medical field, this mechanism that Vinpocetine possesses may be used as a treatment for certain conditions. This includes stroke associated with deficient oxygen supply, Alzheimer’s disease, as well as some brain pathologies. (1)
2. Vinpocetine for energy
In addition with an improved blood circulation to the brain, there would also be higher supply of oxygen and nutrients to the brain cells. And this oxygenation is used for ATP production, the primary energy supply of the cells. With an increase in ATP, there would be more fuel to your neurons that would help sustain your cognitive functions. The user may feel more alert, more energized to do tasks and mental clarity may be improved. (1)
3. Vinpocetine’s influence to several neurotransmitters
Aside from the mechanisms mentioned earlier, Vinpocetine also acts on the body’s neurotransmitter, specifically Acetylcholine, Serotonin, Dopamine, and Noradrenaline.
This potent nootropic influences Acetylcholine levels in the brain and as we all know, this major neurotransmitter is responsible for an individual’s cognition, attention, arousal and reward. With an increase in Acetylcholine levels, we may expect an increased learning ability and an enhanced focus and motivation in doing tasks.
On the other hand, Serotonin is responsible for an individual’s mood, social behaviour, sleep, memory, and other bodily functions (2) while Dopamine is responsible for one’s memory and learning, mood and attention (3). With an increase in levels of Serotonin and Dopamine, you may have an enhanced cognitive function, increased attention and focus and mostly, an improvement in mood and behaviour.
Noradrenaline levels are also raised. This neurotransmitter is associated with alertness, arousal, and the flight or fight response of the body (4). As a result, Vinpocetine serves to enhance one’s energy and well-being. (5)
4. Promotion of a healthy brain
Vinpocetine also possesses to have anti-inflammatory properties. It acts by reducing the inflammatory mediators and vascular cell adhesion molecules. It also serves to remove toxins and harmful compounds that may damage the brain. Because of these mechanisms, Vinpocetine keeps the brain healthy and functioning efficiently and an enhanced neuronal communication. (5)
How do I maximize the effects of Vinpocetine?
1. Proper Vinpocetine dosage and frequency
As for any drug or supplement you are taking in, it is very important to know the proper dosage, frequency and administration for you to attain the effects that you want to achieve. With the case of Vinpocetine, how much of it do we really need each day? Basically, there is a wide range of suggested doses for Vinpocetine which is between 5 mg to 60 mg. However, it is usually taken at doses 15 mg to 40 mg daily and is divided and taken into two or three multiple administrations.
When starting any new drug or supplement, it would be best to start with the lowest possible effective dose and see how your body reacts to it. With Vinpocetine, you might want to consider starting with a dose of 5 mg and then gradually increasing it over time. Results vary considerably among individuals so find the dose that suits you best. Also, it would be best to consult your doctor or healthcare provider regarding your proper Vinpocetine dosage since an individual’s condition and health status may play a role.
2. Stacking Vinpocetine
Stacking has been a popular practice nowadays. This is done for the purpose of maximizing a drug’s potential and also, in order to yield more positive effects, to synergize each other, or to eliminate or minimize the side effects that the drugs may provide. With the case of Vinpocetine, what are the drugs and supplements that may be used in conjunction with it? If you want a more natural nootropic stack, then the Vinpocetine and Ginkgo Biloba stack may be a great option for you. Both of them potentiate each other’s benefits- whether it be an enhanced cognitive function, improved mood, promotion of a healthier brain, and among many others. They synergize each other thus, leading to a powerful and natural stack.
Another common stack would be combining Vinpocetine with a Racetam drug. An example of which is the Vinpocetine and Pramiracetam stack. Being one of the most potent nootropics, Pramiracetam serves to give a significant boost to one’s cognitive functions such as that of long term memory formation and retrieval. Now with the addition of Vinpocetine, it leaves the user with an enhanced mood, attention and focus. With the two drugs combined, it would be a great study aid for students who are seeking to have an increased learning ability as well as an improved drive and focus to do their tasks.
Stacking supplements greatly depends on your needs and preferences. However, one should have a thorough understanding of the drugs you intend to combine since one might not go well with the other. It would also be best to consult your doctor and healthcare provider first for some formal advice. Is Vinpocetine safe to use?
Generally, Vinpocetine is safe to use and is well-tolerated by majority of the users. Although it poses no danger to the human health, still some people may respond differently and may experience some mild Vinpocetine side effects. This includes headaches, anxiety, nausea, stomach pain, and disturbances in sleep. (6)
Where can I purchase Vinpocetine?
It is available over the counter, you do not need any prescription from your doctor in order to buy it. Buy Vinpocetine now
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(1) http://www.braintropic.com/nootropics/vinpocetine/ (2) http://www.medicalnewstoday.com/articles/232248.php (3) http://www.news-medical.net/health/Dopamine-Functions.aspx (4) https://en.wikipedia.org/wiki/Norepinephrine#Central_nervous_system (5) www.ncbi.nlm.nih.gov/pubmed/23136730(6) www.ncbi.nlm.nih.gov/pubmed/12535455
Reviewer: Kathleen R. RN, PT
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Wiki Last Updated: 2016-02-14
Vinpocetine may cause gastrointestinal problems, nausea, headache, dizziness, nervousness, and sleep disturbances.
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