Resveratrol has been proven by many studies to have anti-aging effects, can help increase a person’s life span and improves the health of the brain. Resveratrol is a biologically stilbenoid, known to be a natural phenol substance that is produced in various types of plants. The skin of the grapes, grape seed extract, and other kinds of fruits contain Resveratrol. The Japanese Knotweed is a type plant in which Resveratrol is extracted commercially. Resveratrol can also be sold as a natural supplement. Red wine was known to contain little amounts of it.
Even though this supplement could be absorbed very well in the body, it also has a low bioavailability because it can be quickly metabolized and eliminated. Since the year 1992, experts have been investigating the positive effects of Resveratrol. Recent research suggest that Resveratrol has the ability to act as an anti-inflammatory and anti-oxidant. It has been found to be an ingredient in red wine, but it has been recently highlighted for its long-term benefits. User reviews show that Resveratrol could enhance concentration, mental clarity, and focus when taken alone or in a nootropic stack.
The exact mechanism of action of Resveratrol is still on debate. However, it appears to function as an anti-oxidant. In some clinical studies, Resveratrol shows to be effective in getting rid of free radicals along with numerous other oxidants and appears to aid in activating important cellular anti-oxidant defenses by increasing the production of various internal enzymatic anti-oxidants such as catalase, glutathione, and many more. It has also been discovered to stop low density lipoprotein (LDL) oxidation.
It is important to keep in mind that the mechanisms of action of this type of supplement highly depends on the dosage. Resveratrol effectively functions as an anti-oxidant when taken at higher doses. There are numerous other research studies that suggest how Resveratrol may work, however, more thorough investigations are needed in order to prove their claim. Resveratrol was thought to cause opening or widening of blood vessels or vasodilation and inhibit the aggregation of platelets. This can be done following the production of Nitric Oxide.
Norepinephrine is considered to be one of the adrenal hormones that causes mental alertness and increases the person’s perceptual awareness and attention span. Resveratrol effects on enhancing cognition was thought to be due to the release of norepinephrine at moderate levels. This explains why users experience a boost in their mental stamina and concentration after taking this supplement. Resveratrol is also known to be a serotonin agonist and a Monoamine Oxidase (MAO) inhibitor. Therefore, it could help enhance a person’s mood and sleep quality, and reduce the feelings of anxiety.
The most popular benefits of this supplement is that it can extend the life span of some cells by as much as seventy percent. Resveratrol has been found by some experts to have the ability to cause changes in the expression of genes which might result to significant increase of life span in human beings. These effects were thought to be due to the fact that this supplement can mimic the impacts of low calorie diet in the function of cells. This can lead to a decreased rate of aging, enhanced physical endurance, increased sensitivity to insulin, and increased cellular energy production.
There are some research studies that claim that Resveratrol could help reduce a person’s weight. According to these studies, Resveratrol stimulates the expression of adiponectin, which a hormone that is known to have the ability to fight against insulin resistance and possess anti-obesity properties. Some evidences show that Resveratrol also has the ability to prevent the formation of fat cells and speed up the body’s metabolism.
LDL or low density lipoprotein is considered to be a “bad” cholesterol; an increase in amount of this lipoprotein could lead to heart disease. Resveratrol has been found to decrease low density lipoprotein and prevent the formation of plaques in the vessels that cause the arteries to harden and maintains the blood pressure at lower levels.
Other studies show that Resveratrol can be considered as an anti-cancer supplement. It has been discovered that Resveratrol could suppress the progression of breast cancer in its early stages. It is known to function in preventing the formation of compounds that causes the development of malignant tumors and estrogen from reacting with DNA molecules.
When Resveratrol was investigated as an ingredient of red wine, it was found to provide some promising effects in fighting against age-related diseases such as neuro-degenerative disorders and inflammation. Hardening of the blood vessels and inflammation are thought to trigger the development of Alzheimer’s disease. The most astounding benefit that a person can get from taking this type of supplement is the potential reduction of inflammation, because this is considered to have a primary role in every type of disease we experience.
According to some user reviews, Resveratrol does not seem to cause any negative effects and is very well-tolerated by most users. As a matter of fact, taking a dose of 5 grams (definitely not recommended) could lead to some negative reactions including nausea and mild gastrointestinal upset. There have been no life-threatening effects reported following the use of this supplement.
As of today, there are still no established dose for Resveratrol and the medical community has not yet provided a guideline about the proper way of using it. Some research studies and evidences show that the most acceptable dose for otherwise healthy adult individuals is anywhere between 100 mg and 500 mg. As for those individuals who are not healthy and are suffering from certain conditions, and wants to improve their life span, cardiovascular health, as well as insulin sensitivity, the most acceptable and effective dose is 10 mg a day.
Like any other drugs and supplements, it is always safe to start at the lowest effective dose and gradually increase the dose once you have become familiar with the effects. Even though there have been no reported negative effects associated with the use of this supplement, it is always better to be safe than sorry. Before deciding to take Resveratrol, be sure to contact your physician first.References:
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