Piperine, or black pepper, is a component of some nootropic stack that that offers beneficial effects such as enhancing a person’s cognitive performance and increasing the effects of other smart drugs. It is a natural supplement and an organic compound that is considered to be part of a lipid family, or an alkaloid (one of a large group of organic, basic substances found in plants; are usually bitter in taste and are characterized by powerful physiologic activity). Piperine has been found to enhance mood, improve memory function, reasoning skills, and increase attention. It is additionally one of the sharp-tasting constituents of the fruit of the Piper nigrum plants or pepper vine. Indeed, this concentrate is the thing that gives peppers their spicy taste and it likewise enhances the absorption of various nutrients.
Piperine was discovered way back in 1819 when it was extracted from the fruits of the pepper vine plant. Piperine has been used in different forms of traditional remedy, like Ayurvedic medicine because of its ability to treat gastrointestinal inflammation, pain, distress, and other disorders. This supplement constitutes 5 to 9 percent of both white and black pepper, and is usually mixed with a geometric isomer called chavicine. Interestingly enough, the pepper vine plant is the primary source of both the white and black pepper grains.
Helping increase the absorption of numerous nutrients is one of the most interesting functions of this supplement. Not only does Piperine increase the absorption of nutrients, but it also has the ability to improve the bioavailability of these supplements. Some studies has proven this claim to be true since researchers discovered that Piperine increases the absorption of CoQ10 by about 30 percent, and enhances the bioavailability of this supplement by more than 20 times.
Another interesting fact about this supplement is its apparent thermogenesis effects. Naturally, this would be something which was associated only with the reduction of weight; however, Piperine plays an important role in assisting the body to use the food we partake every day. In other words, Piperine increases the metabolic processes in our body, thus normalizing the mode of transportation of nutrients to the blood. It was even known to function in numerous forms of unrelated processes such as reducing inflammation and pain, as well as fighting against arthritis.
According to a study in the Journal of Traditional Medicine, Piperine has the ability to control behavior and provides positive effects in memory. Numerous studies have been conducted in order to prove Piperine’s effectiveness in enhancing the cognitive processing of humans. It was known that Piperine functions in a similar fashion as Monoamine Oxidase Inhibitors (MAO inhibitors) since its ability to enhance performance seems to be mediated by monoamine neurotransmitters. This can result to increased levels of Serotonin and Dopamine activity, leading to mood enhancement and improvement of performance.
The primary benefit of Piperine is “bio enhancement”, which is enhancing the absorption of nutrients from the intestines. It was known to be beneficial to people who are suffering from malnutrition and malabsorption. Even though Piperine is helpful in enhancing the absorption of various nutrients, evidences have shown that it is helpful with selenium, CoQ (coenzyme Q10), Vitamin C, Vitamin A, and beta-carotene. Numerous nootropic users were asked about the impacts of Piperine to them; they stated that this supplement multiplies the effects of the compounds Racetam, Modafinil, and Noopept on brain power.
It was hypothesized by some researchers that Piperine could reduce the chances of development and progression of gouty arthritis by blocking the formation of uric acid crystals. Some experts claim that Piperine can likewise work as an immunomodulator. This means that when our immune system cannot function well, this supplement would take place and helps reduce general inflammatory response. It was thought that Piperine functions by inhibiting the communication of lymphocytes in the immune system which slows down their action.
A study conducted last 2008 about Piperine indicated that it has some anti-cancer properties. The study reported that this supplement has the ability to stop the growth of colon cancer cells that were grown in a laboratory. However, this is just one study and a lot is needed in order to prove this claim.
Some research suggests that Piperine could also work as an anti-depressant. Neurotransmitters Serotonin and Dopamine are sometimes deficient in individuals who are suffering from depressive disorders since these powerful brain chemicals are thought to enhance general feelings of well-being. In general, Dopamine plays an important role in executive function by increasing a person’s focus and attention span. An increased level of Dopamine can lead to greater productivity results and enhanced motivation. One study concluded that Piperine could increase the activity levels of Serotonin and Dopamine in the central nervous system. This means that this supplement could enhance cognitive function and improve the feelings of well-being.
Piperine is generally considered to not cause any harm to users. However, a lot of questions regarding this supplement were left unanswered. One example is it can increase the effects of some drugs and supplements which are already in use. Unless you have already consulted your physician or any qualified medical professional, it is highly recommended not to take this supplement in combination with any other prescription drugs.
Piperine is a supplement that has the ability to boost the effects of numerous other medications, cognitive enhancers, and supplements. It was known to increase the absorption of supplements such as CoQ10, and Vitamin C. There may be some benefits that this supplement can offer when combined with other nootropics. However, this can also lead to the occurrence of some unwanted effects. On the off chance that you choose to add Piperine to your Nootropic stack, it would be prudent to take it in combination with one nootropic at a time in order to gage its effects to each supplement. In this way, you would be able to track how it influences each nootropic you are using.
You should always keep in mind that Piperine is a very potent supplement. Experts believe that dosages above 15 mg per day could affect the metabolism and absorption of numerous supplements and medications. Therefore, you should be cautions in taking this in combination with other drugs, supplements, and medications. It is advisable to start at a lower dose between 5 and 10 mg per day. Once you have become familiar with its effects, gradually increase it to a higher tolerable dose. Consult a physician or a drug specialist before deciding to add this supplement to your nootropic stack.References:
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