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P21 Review

P21 Review P21 is also known as cyclin-dependent kinase inhibitor 1 or CDK-interacting protein 1. From the name itself, it is a cyclin-dependent kinase inhibitor that promotes cell cycle arrest in response to various stimuli and serves to function both as a sensor and effector of multiple anti-proliferative signals1. It primarily acts by binding and inhibiting the activity of cyclin-CDK2, -CDK1, and -CDK4/6 complexes. Moreover, P21 is greatly influenced by the tumor suppressor protein p53 which lead to the discovery as to how cells stop dividing afters exposure to damaging agents such as radiation2. With regards to HIV infection, P21 mediates the resistance of hematopoietic cells thus, preventing the integration of the virus3. It is also known as -.
P21
Also Known -
Description P21 is also known as cyclin-dependent kinase inhibitor 1 or CDK-interacting protein 1. From the name itself, it is a cyclin-dependent kinase inhibitor that promotes cell cycle arrest in response to various stimuli and serves to function both as a sensor and effector of multiple anti-proliferative signals1. It primarily acts by binding and inhibiting the activity of cyclin-CDK2, -CDK1, and -CDK4/6 complexes. Moreover, P21 is greatly influenced by the tumor suppressor protein p53 which lead to the discovery as to how cells stop dividing afters exposure to damaging agents such as radiation2. With regards to HIV infection, P21 mediates the resistance of hematopoietic cells thus, preventing the integration of the virus3.
Typical Dose
Stacks
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Benefits and Effectiveness


Wiki Last Updated: 2016-02-14

P21 Dosage



Side Effects

There has been no reported side effects yet associated with P21 usage.

No article available.


Results & Experiences

No data available

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