GABA, also known as Gamma-Aminobutyric Acid, is an amino acid produced in the brain from Vitamin B6 and another amino acid called Glutamate. This supplement is often sold as a dietary aid and its claim-to-fame is that it can reduce anxiety thus, resulting in feelings of calmness. Other benefits include its ability to improve concentration, sleep, and memory functions as well as boosting Alpha Brain waves. However, some sources claim that taking GABA alone is not an effective anxiolytic in itself because it does not cross the blood-brain barrier and should therefore be stacked with compounds known to increase GABA levels in the brain- esepcially Picamilon and Phenibut. The degree to which this acts as a nootropic is somewhat controversial.
GABA is categorized under GABAergics.
It is also known as Gamma-Aminobutyric Acid.
Also KnownGamma-Aminobutyric Acid
DescriptionGABA, also known as Gamma-Aminobutyric Acid, is an amino acid produced in the brain from Vitamin B6 and another amino acid called Glutamate. This supplement is often sold as a dietary aid and its claim-to-fame is that it can reduce anxiety thus, resulting in feelings of calmness. Other benefits include its ability to improve concentration, sleep, and memory functions as well as boosting Alpha Brain waves. However, some sources claim that taking GABA alone is not an effective anxiolytic in itself because it does not cross the blood-brain barrier and should therefore be stacked with compounds known to increase GABA levels in the brain- esepcially Picamilon and Phenibut. The degree to which this acts as a nootropic is somewhat controversial.
GABA or Gamma-Aminobutyric Acid is the principal inhibitory neurotransmitter of our body's Central Nervous System. As an inhibitory neurotransmitter, this implies that GABA acts by reducing the activity of our neurons such as those associated with overexcitement or heightened state of excitability. It also regulates an individual's muscle tone. Although GABA has been classified as an amino acid, it does not work like one since it is not involved in the protein building process. (1)
Since it is inhibitory in nature, GABA is a known anxiolytic (anti-anxiety supplement). It promotes feelings of calmness, reduces stress, anxiety and nervousness, can increase focus and concentration and can also be used as a sleeping aid. In addition, GABA works by balancing chemicals in the brain such as adrenaline and noradrenaline. Epinephrine, also known as adrenaline, is the neurotransmitter involved in our body's “fight or flight" response and provides our muscles the energy to respond quickly and more effectively when faced with a threat (2). Meanwhile, norepinephrine is the neurotransmitter also referred to as the stress hormone. As the name implies, it is responsible for our body's ability to respond to stress and is also involved in the “fight or flight" response. Norepinephrine increases a person's breathing rate and heart rate, thus increasing blood circulation. GABA balances and regulates the levels of neurotransmitters which then result in a calm body and state of mind. In contrast, low levels of GABA have been associated with feelings of restlessness, depression, anxiety, and excessive stress.
Is GABA a Nootropic?
As for GABA's nootropic effects, it works by increasing the level of productive alpha waves in the brain which leads to enhanced focus and mental flow. It also serves to enhance the communication between one neuron to another. With this one may experience enhanced cognitive performance such as improved attention and concentration. GABA even serves to aid in the release of chemicals that can help fight pain.
On the other hand, GABA also plays to be beneficial among athletes, bodybuilders, active individuals, or even to people who want to lose fat. This is because this amino acid actually supports the production of other hormones needed for building muscle cells. It has been found that GABA increases strength and muscle gains, improves athletic performance and increases fat loss. Unlike other fat loss products and supplements, GABA does not behave like a stimulant, instead, it supports the production of hormones that help build lean muscle mass. As a result, your body becomes more thermogenic and can boost metabolism since additional muscle mass puts greater caloric demands on the body.
Supplementation with GABA alone might not be that effective. Why? It is because GABA supplements may not able to cross the blood brain barrier easily when taken orally. Because of this, there is no guarantee that you would increase GABA levels in the brain. Despite that, there is still good news. Since GABA supplements cannot enter the human brain easily, scientists have discovered that several supplements can actually increase GABA concentration in the brain. This includes L-Theanine, Phenibut and Picamilon.
L-Theanine, a naturally occurring amino acid in green tea leaves is considered to be a GABA precursor that promotes relaxation while enhancing focus. It has shown to be a promising nootropic used as a study aid and a general mood enhancer. Even though it is regarded to be a nonessential amino acid and is no vital to support human life, it still poses to have important benefits to the human brain. Phenibut on the other hand, is a modified version of GABA. The only difference that lies is that the structure of Phenibut is generally that of GABA's but has an additional phenyl group in it. Because of this, Phenibut can easily cross the blood-brain barrier while GABA can't. Phenibut acts just like GABA by directly influencing and activating the GABA receptors on certain synapses between neurons. It is known to be non-selective, meaning, it targets both GABA-A and GABA-B receptors. Because of this, you will feel relaxed and less stressed. Now, Picamilon is a combination of Niacin and GABA. Niacin is also referred to as Vitamin B3 and just like the other B complex vitamins, it is vital for the storage and production of energy. It also serves to have antioxidant properties and keeps the body healthy by preventing damage to the tissues. If there is insufficient supply of needed Niacin levels, Pellagra may result (3). When Picamilon reaches the brain, it then breaks down into GABA.
What should You consider before taking GABA?
It is important for any drug or supplement to be taken at the right amount and frequency for it to produce the desired effects while possibly eliminating or minimizing the undesired ones. Generally, a daily dose of 3 grams to 5 grams is recommended. This dose may be taken all at once or can be divided and administered into multiple administrations within the day for a more constant and sustained release of benefits. When taking GABA for fat loss, take the supplement 2 hours before sleep. It is also important to note not to take GABA with a protein source since it can affect proper digestion.
Additionally, it would be best to start off with the lowest possible dose to see how you respond and then gradually increasing it over time. You might also want to consider consulting your doctor or healthcare provider first since your personal condition and health status may play a role. The use of GABA has been considered safe and well tolerated to use. Since there is not enough evidence on GABA's safety among pregnant and breast feeding women, it would be best to avoid its use with this specific population.
Where should you buy GABA Online?
You can purchase GABA online as it is available over the counter and thus does not require prescription from a doctor. Buy GABA now with our link to make sure you are getting the best rate, potency, and safe version of this supplement.
Although GABA appears to be potentially safe and well-tolerated, some side effects would include being overly relaxed, so avoid driving a vehicle or operating heavy machinery. Also, the possibility of changes in heart rate and breathing patterns may appear, but should subside quickly.