Cerebrolysin is one of the most interesting nootropic drugs known to have a lot of positive effects in terms of enhancing cognitive function. It is a natural compound produced through a standardized and safe enzymatic process by using pig’s brain proteins (also known as porcine). Cerebrolysin is currently undergoing extensive research studies in various other countries all over the globe and it has been thoroughly investigated by many members of the nootropic community. On the other hand, there 2 main factors as to why Cerebrolysin is not widely used as a nootropic drug. Firstly, it is made out of pig’s brain and is non-vegetarian. Secondly, in order to produce its positive effects, this drug has to be administered via injection.
According to some experts, Cerebrolysin is an injectable protein-based solution that contains a generous amount of neuropeptides. Neuropeptides are tiny molecules and biologically active brain peptides that are needed by the neurons in order to have a constant communication with each other. The astounding characteristic about these peptides is that they could pass through the blood-brain barrier and functions directly upon neurons. Even though Cerebrolysin has some promising effects and has been approved by many countries around the world, the evidences available are still few and a lot are needed in order to prove its effectiveness.
The primary effect of Cerebrolysin is to help fight against Alzheimer’s disease. One of the most amazing functions of this supplement is to delay the progression of the disease instead of reducing the symptoms by attacking the main cause and “heal” the disease. In order to be successful in accomplishing this task, Cerebrolysin has a lot of various mechanisms of action which includes acting as both a neurotrophic and neuroprotective agent.
By acting as a neurotrophic, Cerebrolysin specifically signals nerve cells to differentiate, grow, as well as survive. These actions are exerted on the neurons of the dorsal root ganglia (part of the spinal cord that contains the cell bodies of sensory or afferent neurons) of the spinal cord. Cerebrolysin also functions by causing neurogenesis or the production of new neurons, specifically in the hippocampus area, which is the elongated ridges on the floor of each lateral ventricle of the brain, thought to be the center of emotion, memory, and the autonomic nervous system. All of the information that has been processed inside the brain goes through the hippocampus, which explains why this area is greatly affected in the development of neurodegenerative conditions such as Alzheimer’s disease. In order to be able to make it easier to recall stored memories and increase the rate of memory formation, the function of the hippocampus should be improved.
Before going through the safety of this drug, let us first take a look at the reasons as to why it is being utilized as a means of treatment for Alzheimer’s disease and dementia or as a cognitive enhancer. Vascular dementia is a common form of dementia caused by an impaired supply of blood to the brain, such as may be caused by a series of small strokes. Cerebrolysin is known to be effective in treating this type of disease. This is such a good news since there has been no known treatment for vascular dementia. Furthermore, this supplement has been discovered to enhance the processing of memory, improve concentration and mood in patients who are suffering from vascular dementia.
Amyloids are plaque formations inside the brain tissue and are known to have a relation in the development of Alzheimer’s disease. Some research studies discovered that Cerebrolysin has the ability to reduce the levels of amyloid build-up inside the brain. When there is too much accumulation of amyloids inside the brain tissue, a person has a high possibility of developing reduced memory capacity as well as impairments in cognitive function. Since Cerebrolysin was thought to reduce and control the progression of this plaque formation, then the progression of the disease could be slowed down as well. As a matter of fact, the primary reason as to why Cerebrolysin has been prescribed for patients who are suffering from dementia or Alzheimer’s disease is to slow down its development when it is first recognized.
Some research studies suggest that those individuals who do not have any underlying cognitive impairments could also benefit from taking this supplement. As mentioned earlier, Cerebrolysin injections has the ability to enhance the rate of neurogenesis inside the brain, which leads to the development of new networks of neurons and new nerve cells. This function primarily affects the hippocampus area of the brain, which is considered by some experts to be the area in which memory encoding occurs. It has been hypothesized that in order to achieve a better synaptic plasticity as well as memory retention, the number of neurons in the hippocampus area should be increased.
The effects of Cerebrolysin in enhancing learning capacity and long-term formation could benefit those individuals with dementia as well as those who do not have any cognitive problems. This supplement could also be helpful for students who do not have memory deficits to achieve high scores in their exams. According to some studies on patients with dementia, daily administration of Cerebrolysin could result to enhancement of short-term memory recall and better mathematical reasoning.
Cerebrolysin was reported by many users to be very safe and does not cause any harm. There have been no safety concerns or toxicity reported following the administration of this supplement. There are no known contraindications or drug interactions. However, there are still some potential negative reactions but these have all been transient, mild, and quite rare. Some of these side effects include dizziness, headache, and heat sensations.
This supplement should not be taken by those individuals who are suffering from kidney problems as well as those who are taking MAO inhibitors or anti-depressants. Pregnant and breast-feeding women should also avoid taking this supplement since there is no enough evidence to prove its safety and how might it affect their children.
At this point of time, there is a very specific method of dosing Cerebrolysin. This includes either being administered via intramuscular injection or intravenous infusion. The treatment generally involves one 5 ml ampoule per day for a period of 5 days. This schedule should be strictly followed by a period of 4 weeks.
This schedule is then followed by a period of two months. During this time, the effects or reactions of Cerebrolysin should be carefully noted. After two months, the cycle of treatment may be repeated again if necessary. It is highly recommended that the procedure of treatment and the administration of this supplement should only be done by a qualified medical professional.References:
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